National Heart, Lung, and Blood Institute. Iron-deficiency anemia.Ĭenters for Disease Control and Prevention. If you recently had a plasma transfusion, your plasma levels may temporarily be higher than normal, in turn lowering your hemoglobin levels. Plasma transfusion: Plasma is the liquid portion of blood, separate from red blood cells, white blood cells, and platelets.This is more likely if your blood test had to be transferred to another location, prolonging its exposure to varying temperatures and delaying the processing time. Mishandling of your blood test: It is possible (although unlikely) that your blood specimen was mishandled.Lipidemia: An excess of fat particles (lipids) in your blood can cause a mistakenly high hemoglobin measurement.Infections: Certain infections, such as cytomegalovirus and pneumonia, can cause red blood cells to clump together, which can make hemoglobin levels appear high.High bilirubin levels could indicate liver disease, gallstones, hemolytic anemia, and Gilbert's syndrome. Bilirubin is the substance that's created when your body breaks down red blood cells. Hyperbilirubinemia: This is characterized by high bilirubin levels.Blood transfusion: The hemoglobin levels from the blood in the transfusion may have been high, thus temporarily giving you high hemoglobin.
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